Description
This ARC funded project will decipher the mechanism(s) underpinning the rapid and extensive membrane remodelling in the Gram-negative bacteria Acinetobacter baumannii, focusing on their predominant biogenesis and remodelling pathways and the interactions with membrane-targeting antimicrobial peptides. Importantly, this project will be the first to address critical knowledge gaps through an integrative systems pharmacology, biophysical and computational approach and will generate critical mechanistic information to expedite the future design of antimicrobial agents that are effective against membrane-remodelled bacterial variants.
Essential criteria:
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords
membrane; pathway; antimicrobial; lipid
School
Biomedicine Discovery Institute (School of Biomedical Sciences)
Available options
PhD/Doctorate
Masters by research
Masters by coursework
Honours
Time commitment
Full-time
Top-up scholarship funding available
No
Physical location
Clayton Campus
Co-supervisors
Prof